Discover all about the supplement that supports muscle function

Discover all about the supplement that supports muscle function
Discover all about the supplement that supports muscle function

You work out for real, in search of the long-awaited defined body – hello, hello, summer project! Great, exercising, whether aerobic or anaerobic, is the way to stay in good shape.




Photo: Istock/Disclosure/Boa Forma

But to improve conditioning and endurance and still protect bones and joints from possible injuries, it is important to take care of the health and strengthening of muscles.

“The human body works in a dynamic balance, that is, every day it undergoes reactions of muscle synthesis and degradation, and this is a natural process. Specifically during physical activity, the organism undergoes a series of metabolic changes and, between them, catabolism takes place, that is, the degradation of muscle protein into amino acids, a necessary process for the supply of energy in the practice of exercise”, explains Fernanda Leme, nutritionist at the consultancy Equilibrium Saúde e Nutrição.

That is, with each push-up, sit-up or squat, your muscle fibers undergo an expected damage, and it is through recovery that they reconstitute themselves. In this reaction, leucine, an amino acid present in foods that are a source of protein, plays an important role, as it activates protein synthesis, promotes muscle gain and increased strength.

To preserve lean mass

And if the goal is to prevent muscle loss and gain more strength and endurance – who doesn’t want to? The good news is the discovery of beta-hydroxy-beta-methylbutyric acid (HMB), a substance produced by the body, via leucine metabolism, or ingested in source supplements, which performs several functions in the body. “Regarding the reduction of muscle damage, it is observed that HMB alters protein turnover, that is, it changes the balance between protein synthesis and protein degradation. What does this mean? That HMB is able to reduce protein breakdown and, consequently, generate a positive turnover, with greater maintenance of lean mass”, says Fernanda.

Extra dose of HMB

Under normal health conditions, HMB is a metabolite produced by the body, but only 5% of the body’s leucine is converted to HMB (which corresponds to 0.2 to 0.4 grams of HMB per day), which is insufficient to support the muscle function.

This is where supplementation has gained relevance, by offering benefits such as increased protein synthesis and, consequently, muscle hypertrophy, reducing protein degradation in muscles after intense physical exercise, collaborating with their recovery, and increasing strength. and muscle functionality.

According to the nutritionist, the consumption of HMB is indicated for both audiences. “Its role in protecting lean mass helps both those who want to increase their muscle volume and those who seek to preserve lean mass – an important factor especially from the age of 50, when the loss of lean mass is accentuated. In women, with the change resulting from menopause, this difficulty can be even greater. The decrease in the amount of lean mass can lead to sarcopenia, which is the loss of muscle volume and strength, and compromise the quality of life.”

For those looking to support muscle function, Vitasay Muscle is a good choice. Thanks to the HMB present in the formulation, the supplement helps to increase muscle strength and endurance and prevent the loss of lean mass and also contributes to the reduction of muscle damage.

The HMB supplement can be consumed by anyone wishing to mitigate protein catabolism. However, its use is mainly indicated for athletes and people who practice physical exercises and seek to improve muscle gain and performance; people with low leucine intake who wish to maintain muscle mass at normal levels and the 50+ public, who seek to inhibit muscle loss, a process that is more pronounced in this age group.

References:

Alvares TS, Meirelles CM. Effects of b-hydroxy-b-methylbutyrate supplementation on strength and hypertrophy. Nutrition Magazine [online]. 2008, v. 21, no. 1, p. 49-61. [Acessado em: 11 maio 2022]. Available at: Epub 02 Apr 2008. ISSN 1678-9865. https://doi.org/10.1590/S1415-52732008000100006.

Baier S, Johannsen D, Abumrad N, Rathmacher JA, Nissen S, Flakoll P. Year-long changes in protein metabolism in elderly men and women supplemented with a nutrition cocktail of beta-hydroxy-betamethylbutyrate (HMB), L-arginine, and L-lysine. JPEN J Parenter Enteral Nutr. 2009 Jan-Feb;33(1):71-82. doi: 10.1177/0148607108322403. PMID: 19164608.

Borack MS, Volpi E. Efficacy and safety of leucine supplementation in the elderly. J Nutri. 2016 Dec;146(12):2625S-2629S. doi: 10.3945/jn.116.230771. Epub 2016 Nov 9. PMID: 27934654; PMCID: PMC5118760.

Durkalec-Michalski K, Jeszka J, Podgórski T. The effect of a 12-week beta-hydroxy-beta-methylbutyrate (HMB) supplementation on highly-trained combat sports athletes: a randomized, double-blind, placebocontrolled crossover study. Nutrients. 2017 Jul 14;9(7):753. doi: 10.3390/nu9070753. PMID: 28708126; PMCID: PMC5537867.

Gepner Y, Varanoske AN, Boffey D, Hoffman JR. Benefits of β-hydroxy-β-methylbutyrate supplementation in trained and untrained individuals. Res Sports Med. 2019 Apr-Jun;27(2):204-218. doi: 10.1080/15438627.2018.1533470. Epub 2018 Oct 22. PMID: 30348016.

Guedes JM, Peluzio MDCG, Rathmacher JA, Leal TF, Júnior MAC, de Carvalho DM, de Oliveira LL, Natali AJ. βhydroxy-β-methylbutyrate supplementation benefits the effects of resistance training on body fat reduction via increased irisin expression in white adipose tissue. Biol Sport. 2021 Mar;38(1):113-121. doi: 10.5114/biolsport.2020.97671. Epub 2020 Aug 21. PMID: 33795920; PMCID: PMC7996383.

Holeček M. Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and musclewasting conditions. J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):529-541. doi: 10.1002/jcsm.12208. Epub 2017 May 10. PMID: 28493406; PMCID: PMC5566641.

Kaczka P, Michalczyk MM, Jastrząb R, Gawelczyk M, Kubicka K. Mechanism of action and the effect of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on different types of physical performance – a systematic review. J Hum Kinet. 2019 Aug 21;68:211-222. doi: 10.2478/hukin-2019-0070. PMID: 31531146; PMCID: PMC6724588.

Kuriyan R, Lokesh DP, Selvam S, Jayakumar J, Philip MG, Shreeram S, Kurpad AV. The relationship of endogenous plasma concentrations of β-Hydroxy β-Methyl Butyrate (HMB) to age and total appendicular lean mass in humans. Exp Gerontol. 2016 Aug;81:13-8. doi: 10.1016/j.exger.2016.04.013. Epub 2016 Apr 20. PMID: 27108182.

Lin Z, Zhao Y, Chen Q. Effects of oral administration of β-hydroxy β-methylbutyrate on lean body mass in older adults: a systematic review and meta-analysis. Eur Geriatr Med. 2021 Apr;12(2):239-251. doi: 10.1007/s41999-020-00409-9. Epub 2020 Oct 8. PMID: 33034021.

Nissen SL, Abumrad, NN. Nutritional role of the leucine metabolite β-hydroxy β-methylbutyrate (HMB). The Journal of Nutritional Biochemistry, vol. 8, Issue 6, 1997, p. 300-311. ISSN 0955-2863. Available at: https://doi.org/10.1016/S0955-2863(97)00048-X .

Oktaviana J, Zanker J, Vogrin S, Duque G. The effect of β-hydroxy-β-methylbutyrate (HMB) on sarcopenia and functional frailty in older persons: a systematic review. J Nutri Health Aging. 2019;23(2):145-150. doi: 10.1007/s12603-018-1153-y. PMID: 30697623.

Pereira IFS, Spyrides MHC, Andrade LMB. Nutritional status of elderly people in Brazil: a multilevel approach. Public Health Notebooks [online]. 2016, v. 32, no. 5 [Acessado em: 12 maio 2022], e00178814. Available at: Epub 03 Jun 2016. ISSN 1678-4464. https://doi.org/10.1590/0102-311X00178814 .

Portal S, Eliakim A, Nemet D, Halevy O, Zadik Z. Effect of HMB supplementation on body composition, fitness, hormonal profile and muscle damage indices. J Pediatr Endocrinol Metab. 2010 Jul;23(7):641-50. doi: 10.1515/jpem.2010.23.7.641. PMID: 20857835.

Rathmacher JA, Pitchford LM, Khoo P, Angus H, Lang J, Lowry K, Ruby C, Krajek AC, Fuller JC, Sharp RL. Longterm effects of calcium β-hydroxy-β-methylbutyrate and vitamin D3 supplementation on muscle function in older adults with and without resistance training: a randomized, double-blind, controlled study. J Gerontol A Biol Sci Med Sci. 2020 Oct 15;75(11):2089-2097. doi: 10.1093/gerona/glaa218. PMID: 32857128; PMCID: PMC7566440.

Wilson JM, Fitschen PJ, Campbell B, Wilson GJ, Zanchi N, Taylor L, Wilborn C, Kalman DS, Stout JR, Hoffman JR, Ziegenfuss TN, Lopez HL, Kreider RB, Smith-Ryan AE, Antonio J. International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB). J Int Soc Sports Nutr. 2013 Feb 2;10(1):6. doi: 10.1186/1550-2783-10-6. PMID: 23374455; PMCID: PMC3568064.

+The best content in your email for free. Choose your favorite Terra Newsletter. Click here!

The article is in Portuguese

Tags: Discover supplement supports muscle function

PREV Ex-wife of president has graffitied house: “death to Bolsonaro”
NEXT LAST MINUTE: Ukraine requests NATO membership in “urgent and emergency nature”
-

-

-

-